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The metabolic fate of purified glucoraphanin in F344 rats

VDAC1 and IP3R mainly act as transmembrane signaling channels, indirectly modulating the threshold for autophagy activation by regulating membrane lipid exchange, ATP permeability, and cellular metabolism [98,99,100]

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3.1.2 Extrinsic pathway As its name suggests, the extrinsic pathway is triggered primarily by extracellular signals mediated by immune system cells, such as lymphocytes or macrophages